McCune Albright Syndrome

Sorry about the appearance of the image... I was not able to invert the colour scheme.

However, this patient presented to our department to determine if osteomyelitis was present in her right upper jaw.  In short, our doctors were unable to decide if the site had osteomyelitis, because of other confounding circumstances such as the patient's recent dental work in the same area.  It was tough because they were unsure if there was some type of odontogenic infection occurring as well.  Plus the extent of the underlying bone that was involved in this infection was difficult to resolve given the patient's underlying bony lesions.  The sulphur colloid (bone marrow images) and the delayed In-111 WBC images are not included for viewing because the interesting point about this case, is the actual total body bone scan itself.

McCune Albright Syndrome (polyostotic fibrous dysplasia) is a genetic disorder that affects the bones and pigmentation of the skin.  It is not a common disorder and the exact number of cases in the United States and internationally is not known.  However what is interesting are the multiple abnormal foci of increased activity noted within the bones, this in keeping with the nature of the syndrome. Anyway I thought this was more interesting than the osteomyelitis component of this case.